Descripción del título
This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases
Monografía
monografia Rebiun18701486 https://catalogo.rebiun.org/rebiun/record/Rebiun18701486 cr c||||||||| 170207s2017 gw o 001 0 eng d 9783319500478 978-3-319-50047-8 10.1007/978-3-319-50047-8 doi CBUC 991050720409706706 UPVA 996887586603706 UAM 991007668060004211 UR0408468 UAL spa UAL rdc 616.9041 23 The Actin Cytoskeleton and Bacterial Infection edited by Hans Georg Mannherz Cham Springer International Publishing Imprint: Springer 2017 Cham Cham Springer International Publishing Imprint: Springer 1 recurso en línea 1 recurso en línea X, 242 p X, 242 p Texto (visual) isbdcontent electrónico isbdmedia Springer eBooks Current Topics in Microbiology and Immunology 0070-217X 399 Actin structure and dynamics -- Influence of binary actin-depolymerizing toxins on the microtubule system -- ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling -- Pathogenic mechanisms of actin cross-linking toxins – peeling away the layers -- New concepts on bacterial effectors targeting Rho GTPases -- Interaction of bacterial ADPribosyltransferases with actin -- Yersinia's ways to activate and inactivate actin rearrangements in host cells -- The role of formins in phagocytosis of Borrelia by macrophages This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases Modo de acceso: World Wide Web Medicine Medical microbiology Pharmacology Biomedicine Medical Microbiology Pharmacology/Toxicology Ciencias biomédicas Libros electrónicos Recursos electrónicos Mannherz, Hans Georg SpringerLink (Online service)