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Systems biology / edited by...
A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation of key genes and a presentation of a theory of chemical organisation which provides a new view of the system's structure. The clearly written chapters by experts in the field describe methods applicable to investigating the unique facets of cell culture. The book should be of interest to all those working in cell culture development and drug discovery in pharmaceutical and biotechnology companies as well as in academic institutions. It provides an invaluable resource for students and researchers in biotechnology, cell culture, genomics and bioinformatics
Monografía
monografia Rebiun25829105 https://catalogo.rebiun.org/rebiun/record/Rebiun25829105 m o d cr cn||||||||| 080104s2007 ne a ob 000 0 eng d 173516341 228152999 228153000 228377008 320966053 433191900 437240713 648255358 722576079 756425323 985038965 994689752 1005751946 1020005407 1035668649 1044145765 1044230877 1056323024 1056373084 1066996828 1077279609 1078838026 1086865250 1086908341 1110861012 1110941120 1112525278 1125437460 9781402052521 1402052529 1402052510 Cloth) 9781402052514 Cloth) 6610864381 9786610864386 10.1007/1-4020-5252-9. doi AU@ 000042137817 AU@ 000043265346 AU@ 000054428398 DEBSZ 430687486 NZ1 11680981 NZ1 12052298 978-1-4020-5251-4 Springer http://www.springerlink.com GW5XE eng pn GW5XE GW5XE YDXCP TEX OCLCQ CEF OCLCQ UAB WAU WTU AU@ CNTRU N$T E7B IDEBK OCLCO EBLCP OCLCQ A7U OCLCQ OCLCF BEDGE OCLCQ DEBSZ NUI OCLCQ VT2 Z5A OTZ OCLCQ ESU CASUM MERER OCLCO STF OCLCQ U3W OCLCQ WYU ICG UWO YOU OCLCO CANPU OCLCA OCLCQ OCLCO W2U DCT ZHM ERF OCLCQ SFB OCLCA QH lcco RM lcco SCI 017000 bisacsh PSBC. bicssc 571.6 22 Systems biology edited by Mohamed Al-Rubeai and Martin Fussenegger Dordrecht Springer 2007 Dordrecht Dordrecht Springer 1 online resource (viii, 423 pages) illustrations 1 online resource (viii, 423 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Cell engineering v. 5 Includes bibliographical references Structural Genomics -- RNA Interference in Haematopoietic and Leukaemic Cells -- Genomics and Proteomics of Chinese Hamster Ovary (CHO) Cells -- The Unfolded Protein Response -- Engineering of Cell Proliferation Via Myc Modulation -- The Molecular Response(s) During Cellular Adaptation to, and Recovery from, Sub-Physiological Temperatures -- Molecular Response to Osmotic Shock -- Metabolomics -- Metabolic Flux Analysis of Mammalian Cells -- Metabolic Engineering -- Chemical Organisation Theory -- Prokaryotic Systems Biology A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation of key genes and a presentation of a theory of chemical organisation which provides a new view of the system's structure. The clearly written chapters by experts in the field describe methods applicable to investigating the unique facets of cell culture. The book should be of interest to all those working in cell culture development and drug discovery in pharmaceutical and biotechnology companies as well as in academic institutions. It provides an invaluable resource for students and researchers in biotechnology, cell culture, genomics and bioinformatics Cell physiology Biological systems Cell Engineering Cell Physiological Phenomena Systems Biology SCIENCE- Life Sciences- Cell Biology. Biomédecine. Sciences de la vie. Biological systems. Cell physiology. Electronic books Al-Rubeai, Mohamed 1948-) Fussenegger, Martin Springer e-books Springer e-books Print version Systems biology. Dordrecht : Springer, 2007 9781402052514 1402052510 (DLC) 2007425735 (OCoLC)77482079 Cell engineering v. 5