Descripción del título
Epitranscriptomics / Stefan...
This book reviews a novel and exciting ld of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism's cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person's biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification
Monografía
monografia Rebiun28910924 https://catalogo.rebiun.org/rebiun/record/Rebiun28910924 m o d cr cnu---unuuu 210731s2021 sz o 000 0 eng d 9783030716127 electronic bk.) 3030716120 electronic bk.) 3030716112 9783030716110 10.1007/978-3-030-71612-7 doi AU@ 000069686092 UPNA0538799 UPVA 997818446903706 UAM 991008097538204211 UCAR 991008232596404213 UR0531524 YDX eng rda YDX GW5XE YDX OCLCO N$T OCLCF (S PSAK bicssc SCI029000 bisacsh PSAK thema 572.8/845 23 Epitranscriptomics Stefan Jurga, Jan Barciszewski, editors Cham, Switzerland Springer 2021 Cham, Switzerland Cham, Switzerland Springer 1 online resource 1 online resource Text txt rdacontent computer c rdamedia online resource cr rdacarrier RNA Technologies 2197-9731 v. 12 This book reviews a novel and exciting ld of cellular and molecular biology called epitranscriptomics, which focuses on changes in an organism's cells resulting from the posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Exploring the mechanisms underlying RNA modifications and RBP function is an emerging area of biomedical research, taking the study of gene regulation a step beyond epigenetics. This book reveals that the RNA molecule is not just an information-carrying molecule with some secondary structures. Accordingly, how RNA is modified, regulated, packaged, and controlled is an important aspect. Leading experts address questions such as where the over 170 distinct posttranscriptional RNA modifications are located on the genome, what percentage of mRNAs and noncoding RNAs these modifications include, and how an RNA modification impacts a person's biology. In closing, the book reviews the role of RNA modifications and RBPs in a variety of diseases and their pathogenesis. Addressing some of the most exciting challenges in epitranscriptomics, this book provides a valuable and engaging resource for researchers in academia and industry studying the phenomena of RNA modification Genetic transcription ARN Genetic transcription. ARN Electronic books Jurga, Stefan editor Barciszewski, Jan editor Print version 3030716112 9783030716110 (OCoLC)1237634398 RNA technologies v. 12. 2197-9731