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Nongenotoxic Carcinogenesis...
The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic". On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field
Monografía
monografia Rebiun38686880 https://catalogo.rebiun.org/rebiun/record/Rebiun38686880 m o d cr mnu---uuaaa 130125s1994 gw ob 001 0 eng 934994032 936316832 968661878 1058407972 1086548199 9783662030226 electronic bk.) 3662030225 electronic bk.) 9783662030240 3662030241 3662030225 10.1007/978-3-662-03022-6 doi AU@ 000051667145 NZ1 15005768 NZ1 15327695 AU@ 000065523530 AU@ eng pn AU@ GW5XE OCLCF UA@ COO OCLCQ EBLCP OCLCQ YDX UAB OCLCQ LEAUB OCLCQ UKAHL OCLCO OCLCQ OCLCO OCLCL OCLCQ OCLCL MJCL bicssc MED062000 bisacsh MJCL thema 616.994 23 https://id.oclc.org/worldcat/ddc/E3bH7YMqBw7DXC6pMXBTJd6kXv Cockburn, Andrew Nongenotoxic Carcinogenesis edited by Andrew Cockburn, Lewis Smith Berlin, Heidelberg Springer Berlin Heidelberg 1994 Berlin, Heidelberg Berlin, Heidelberg Springer Berlin Heidelberg 1 online resource (xii, 240 pages) 1 online resource (xii, 240 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Ernst Schering Research Foundation Workshop 0947-6075 10 Includes bibliographical references and index 1 Nongenotoxic Chemical Carcinogens: Evidence for Multiple Mechanisms -- 2 Oxidative Damage and Carcinogenesis -- 3 DNA Damage by Free Radicals. Mechanism, Meaning and Measurement -- 4?2u-Globulin Mediated Male Rat Kidney Carcinogenesis -- 5 Nongenotoxic Mechanisms in Thyroid Carcinogenesis -- 6 Nongenotoxic Carcinogenesis in the Liver -- 7 Compensatory Cell Proliferation, Mitogen-Induced Liver Growth and Hepatocarcinogenesis in the Rat -- 8 The Role of Genotoxic and Nongenotoxic Agents in Multistage Carcinogenesis of Mouse Skin -- 9 Liver Tumor Promotion and Breast Cancer Chemoprevention: Common Mechanisms -- 10 Peroxisome Proliferation and Hepatocarcinogenesis -- 11 Peroxisome Proliferators Mimic an Endogenous Inducer and Inactivate a Transcriptional Repressor in Bacillus megaterium -- 12 The Interaction of Genes and Hormones in Murine Hepatocarcinogenesis -- 13 Evaluating Carcinogenic Risks The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic". On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field English Medicine Toxicology Oncology Biochemistry Medicine Toxicology Medical Oncology Biochemistry Médecine Toxicologie Cancérologie Biochimie medicines (material) toxicology. biochemistry. medicine (discipline) Biochemistry. Medicine. Oncology. Toxicology. Smith, Lewis Print version 9783662030240 Ernst Schering Research Foundation workshop 10