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Organ-Selective Actions of ...
Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity
Monografía
monografia Rebiun38708424 https://catalogo.rebiun.org/rebiun/record/Rebiun38708424 m o d cr mnu---uuaaa 130220s1995 gw o 000 0 eng 934999070 936319665 968669588 1086478357 9783662091531 electronic bk.) 3662091534 electronic bk.) 9783662091555 3662091550 3662091534 10.1007/978-3-662-09153-1 doi AU@ 000051655923 NZ1 15006490 NZ1 15309185 AU@ eng pn AU@ GW5XE OCLCF UA@ COO OCLCQ EBLCP OCLCQ YDX UAB OCLCQ LEAUB OCLCQ OCLCO OCLCA UKAHL OCLCO OCLCQ OCL OCLCO OCLCL OCLCQ MJ bicssc MED045000 bisacsh MJ thema 616 23 Baird, D. T. Organ-Selective Actions of Steroid Hormones edited by D.T. Baird, G. Schütz, R. Krattenmacher Berlin, Heidelberg Springer Berlin Heidelberg 1995 Berlin, Heidelberg Berlin, Heidelberg Springer Berlin Heidelberg 1 online resource (xiv, 184 pages) 1 online resource (xiv, 184 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF Ernst Schering Research Foundation Workshop 0947-6075 16 1 Development of Tissue-Selective Estrogen Receptor Modulators -- 2 Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Interactions with Second Messenger Signaling Pathways -- 3 Analysis of Genetically Altered Mice Without Glucocorticoid Receptor -- 4 Organ-Selective Actions of Tamoxifen and Other Partial Antiestrogens -- 5 Progestin Regulation of Cell Proliferation in the Breast and Endometrium -- 6 Central Versus Endometrial Effects of Antiprogestins: Is Endometrial Selectivity Possible? -- 7 Androgen Action on the Bone -- 8 General Principles of Vitamin D Action and Mechanism-Based Search for Analogs with Specific Actions -- 9 Organ-Specific Actions of Vitamin D Analogs: Relevance of Rapid Effects -- Previous Volumes Published in this Series Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity Medicine Human genetics Internal medicine Tissue-specific antigens Hormones- physiology Steroids- physiology Hormone Antagonists- pharmacology Vitamin D- pharmacology Organ Specificity Medicine Internal Medicine Médecine Génétique humaine Médecine interne Antigènes spécifiques de tissus medicines (material) medicine (discipline) Tissue-specific antigens. Human genetics. Internal medicine. Medicine. Congress proceedings (reports) Conference papers and proceedings. Conference papers and proceedings. Actes de congrès. Schütz, G. Krattenmacher, R. Print version 9783662091555 Ernst Schering Research Foundation workshop 16