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Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently, little hope of effective therapies capable of slowing the disease process or preventing its occurrence was apparent. With recent advances in the genetics and molecular biology of the disease processes and the demonstration of the involvement of multiple aetiological factors, however, real chances are now appearing for the identification of preventive drugs. In this discussion, experts from disciplines ranging from molecular genetics to the clinic provide review and novel data concerning the aetiology of AD and the establishment of drugfinding screening methods
Monografía
monografia Rebiun22056902 https://catalogo.rebiun.org/rebiun/record/Rebiun22056902 m o d cr un||||a|a|| 111108s1996 gw a ob 001 0 eng d 605922359 608478743 968456388 1001505584 1012453767 1016308400 1023089030 1036785439 1046617693 9783662032480 electronic bk.) 3662032481 electronic bk.) 9783662032503 print) 3662032503 print) 3540609091 9783540609094 0387609091 New York) 9780387609096 New York) 10.1007/978-3-662-03248-0 doi AU@ 000051653437 NZ1 15005811 NZ1 15301184 OCLCE eng pn OCLCE OCLCQ OCLCO GW5XE OCLCF UA@ COO OCLCQ EBLCP OCLCQ YDX UAB OCLCO OCLCA OCLCQ OCLCA dlr 616.8/31 20 44.90 bcl YG 4000 rvk YG 4005 rvk Alzheimer's disease etiological mechanisms and therapeutic possibilities J.D. Turner, K. Beyreuther, F. Theuring, editors Berlin New York Springer ©1996 Berlin New York Berlin New York Springer 1 online resource (xiii, 213 pages) illustrations 1 online resource (xiii, 213 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier Ernst Schering Research Foundation workshop 17 Includes bibliographical references and index 1 Alzheimer's Disease With and Without Familial Aggregation: A Case for Phenotypical Similarity -- 2 The Vascular Dementias and Cerebrovascular Involvement in Alzheimer's Disease -- 3 The Genes Involved in Alzheimer's Disease -- 4 In Vivo Biology of Amyloid Precursor Protein/Amyloid Precursor-like Proteins and Transgenic Animal Models of Alzheimer's Disease -- 5 Molecular Processing Pathways of?-Amyloid Precursor Protein: Therapeutic Implications -- 6 Regulation of Amyloid?-Protein Precursor Processing by Cell Surface Receptor Ligands and Second Messengers -- 7 Tau Phosphorylation and Dephosphorylation in the Pathogenesis of Alzheimer's Disease -- 8 Cytokines in Alzheimer's and Other Neurodegenerative Diseases -- 9 Inflammation in the CNS and in Alzheimer's Disease -- 10 Protein Modifications and Interactions in Alzheimer's Disease -- 11 Protein Aging and Its Relevance to the Etiology of Alzheimer's Disease -- Previous Volumes Published in this Series Use copy. Restrictions unspecified star. MiAaHDL Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently, little hope of effective therapies capable of slowing the disease process or preventing its occurrence was apparent. With recent advances in the genetics and molecular biology of the disease processes and the demonstration of the involvement of multiple aetiological factors, however, real chances are now appearing for the identification of preventive drugs. In this discussion, experts from disciplines ranging from molecular genetics to the clinic provide review and novel data concerning the aetiology of AD and the establishment of drugfinding screening methods Electronic reproduction. [S.l.] HathiTrust Digital Library 2010. MiAaHDL Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL Alzheimer's disease- Etiology Alzheimer's disease- Chemotherapy Alzheimer Disease- etiology Alzheimer Disease- physiopathology Maladie d'Alzheimer Alzheimer's disease- Chemotherapy Alzheimer's disease- Etiology Ziekte van Alzheimer Etiologie (geneeskunde) Therapieën Alzheimerkrankheit Aufsatzsammlung Kongress Congress Aufsatzsammlung Berlin (1996) Kongreß Electronic books Berlin (1996) Turner, J. D. Jonathan D.) 1951-) Beyreuther, K. Konrad) 1941-) Theuring, F. Franz) Print version (DLC) 96017823 (OCoLC)34584029 Ernst Schering Research Foundation workshop 17